| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1A1 |
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| Ligand | BDBM195591 |
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| Substrate/Competitor | US9333197, Ethoxyresorufin |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | >25000±n/a nM |
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| Citation |  Notte, G Apoptosis signal-regulating kinase inhibitor US Patent US9333197 Publication Date 5/10/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1A1 |
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| Name: | Cytochrome P450 1A1 |
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| Synonyms: | CP1A1_HUMAN | CYP1A1 | CYPIA1 | Cytochrome P450 1A | Cytochrome P450 1A1 | Cytochrome P450 1A1 (CYP1A1) | P450 form 6 | P450-C | P450-P1 |
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| Type: | Protein |
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| Mol. Mass.: | 58177.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04798 |
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| Residue: | 512 |
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| Sequence: | MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPH
LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQS
MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAG
PGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPIL
RYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANV
QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS
DRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKL
WVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEF
SVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS
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| BDBM195591 |
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| US9333197, Ethoxyresorufin |
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| Name | BDBM195591 |
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| Synonyms: | US9216974,Resorufin | US9333197, Resorufin |
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| Type | Small organic molecule |
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| Emp. Form. | C12H7NO3 |
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| Mol. Mass. | 213.1889 |
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| SMILES | Oc1ccc2nc3ccc(=O)cc3oc2c1 |
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| Structure | 
|
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