| Reaction Details |
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 | Report a problem with these data |
| Target | Malate synthase G [C619A] |
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| Ligand | BDBM50152579 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | DNTB-Coupled_Enzyme_Assay |
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| IC50 | 240±n/a nM |
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| Citation |  D3R, DD Sacchettini GlcB D3R D3R Publication Date 6/30/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Malate synthase G [C619A] |
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| Name: | Malate synthase G [C619A] |
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| Synonyms: | MASZ_MYCTO | glcB |
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| Type: | n/a |
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| Mol. Mass.: | 80350.85 |
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| Organism: | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
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| Description: | P9WK16[C619A] |
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| Residue: | 741 |
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| Sequence: | MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDEL
QAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSGVDAEITTTAGPQLVVP
VLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSV
PLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIE
ILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLA
AAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFE
GIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVL
GLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRK
GTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTA
WVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDN
NCQSILGYVVRWVDQGVGASKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRA
SLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRRE
FKARAAEKPAPSDRAGDDAAR
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| BDBM50152579 |
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| n/a |
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| Name | BDBM50152579 |
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| Synonyms: | 4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid | CHEMBL364328 | Sacchettini_2 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H7FO4 |
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| Mol. Mass. | 210.1586 |
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| SMILES | OC(=O)C(=O)CC(=O)c1ccccc1F |
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| Structure | 
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