| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator [179-424,C299A,N323Q] |
|---|
| Ligand | BDBM50147085 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Photometric_Method1 |
|---|
| Ki | 630±n/a nM |
|---|
| Citation |  D3R, DD Abbott Urokinase D3R D3R Publication Date 6/30/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Urokinase-type plasminogen activator [179-424,C299A,N323Q] |
|---|
| Name: | Urokinase-type plasminogen activator [179-424,C299A,N323Q] |
|---|
| Synonyms: | PLAU | UROK_HUMAN | Urokinase |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 27687.84 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00749[179-424,C299A,N323Q] |
|---|
| Residue: | 246 |
|---|
| Sequence: | IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVY
LGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTI
ALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTK
MLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPW
IRSHTK
|
|
|
|---|
| BDBM50147085 |
|---|
| n/a |
|---|
| Name | BDBM50147085 |
|---|
| Synonyms: | 7-METHOXY-8-[1-(METHYLSULFONYL)-1H-PYRAZOL-4-YL]NAPHTHALENE-2-CARBOXIMIDAMIDE | 7-methoxy-8-(1-(methylsulfonyl)-1H-pyrazol-4-yl)-2-naphthimidamide | 8-(1-Methanesulfonyl-1H-pyrazol-4-yl)-7-methoxy-naphthalene-2-carboxamidine | CHEMBL321944 | uPa_13 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H16N4O3S |
|---|
| Mol. Mass. | 344.388 |
|---|
| SMILES | COc1ccc2ccc(cc2c1-c1cnn(c1)S(C)(=O)=O)C(N)=N |
|---|
| Structure | 
|
|---|
Search and Browse
