| Reaction Details |
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 | Report a problem with these data |
| Target | RNA polymerase sigma factor SigB |
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| Ligand | BDBM226119 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biolayer Interferometry (BLI) Assay |
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| Kd | 11700±5800 nM |
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| Citation |  Vishwanath, S; Banerjee, S; Jamithireddy, AK; Srinivasan, N; Gopal, B; Chatterjee, J Design, Synthesis, and Experimental Validation of Peptide Ligands Targeting Mycobacterium tuberculosis s Factors. Biochemistry56:2209-2218 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| RNA polymerase sigma factor SigB |
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| Name: | RNA polymerase sigma factor SigB |
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| Synonyms: | RNA polymerase sigma factor SigB (σB) | RNA polymerase sigma factor SigB (ϿB) | SIGB_MYCTU | mysB | sigB |
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| Type: | Protein |
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| Mol. Mass.: | 36343.42 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WGI5 |
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| Residue: | 323 |
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| Sequence: | MADAPTRATTSRVDSDLDAQSPAADLVRVYLNGIGKTALLNAAGEVELAKRIEAGLYAEH
LLETRKRLGENRKRDLAAVVRDGEAARRHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGN
LGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLARIKRE
MHQHLGREATDEELAAESGIPIDKINDLLEHSRDPVSLDMPVGSEEEAPLGDFIEDAEAM
SAENAVIAELLHTDIRSVLATLDEREHQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQ
IERDVMSKLRHGERADRLRSYAS
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| BDBM226119 |
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| n/a |
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| Name | BDBM226119 |
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| Synonyms: | ELTPRESDDRHDSGRD | MT6 |
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| Type | Small organic molecule |
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| Emp. Form. | C73H117N27O32 |
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| Mol. Mass. | 1884.8718 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| |
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| Structure | 
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