| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
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| Ligand | BDBM50053679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PIM Kinase Binding Assay |
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| pH | 7.2±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 0.006±n/a nM |
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| Comments | extracted |
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| Citation |  Burch, J; Sun, M; Wang, X; Blackaby, W; Hodges, AJ; Sharpe, A Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use US Patent US9328106 Publication Date 5/3/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-1 |
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| Name: | Serine/threonine-protein kinase pim-1 |
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| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
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| Type: | Protein |
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| Mol. Mass.: | 35681.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11309 |
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| Residue: | 313 |
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| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
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| BDBM50053679 |
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| n/a |
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| Name | BDBM50053679 |
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| Synonyms: | CHEMBL3318853 | US9328106, 115 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22F2N6O2S |
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| Mol. Mass. | 460.5 |
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| SMILES | [H][C@]12CC[C@](CC[C@@H]1N)(O2)c1c(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)cnn1C |r| |
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| Structure | 
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