| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carboxylic ester hydrolase |
|---|
| Ligand | BDBM227566 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cholinesterase Activity Assay |
|---|
| IC50 | 17830±780 nM |
|---|
| Citation |  Aouani, I; Sellami, B; Lahbib, K; Cavalier, JF; Touil, S Efficient synthesis of novel dialkyl-3-cyanopropylphosphate derivatives and evaluation of their anticholinesterase activity Bioorg Chem72:301-307 (2017) |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carboxylic ester hydrolase |
|---|
| Name: | Carboxylic ester hydrolase |
|---|
| Synonyms: | BuChE | Butyrlcholinesterase (BuChE) | Butyrylcholine esterase | Butyrylcholinesterase | Butyrylcholinesterase (BChE) | Butyrylcholinesterase (BuChE) | Butyrylcholinesterase (EqBuChE) | Carboxylic ester hydrolase | butyrylcholinesterase precursor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68842.83 |
|---|
| Organism: | Equus caballus (Horse) |
|---|
| Description: | Q9N1N9 |
|---|
| Residue: | 602 |
|---|
| Sequence: | MQSWGTIICIRILLRFLLLWVLIGNSHTEEDIIITTKNGKVRGMNLPVLGGTVTAFLGIP
YAQPPLGRLRFKKPQSLTKWSNIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTELSEDC
LYLNVWIPAPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALG
FLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPR
SQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEI
LLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFLVY
GAPGFSKDNNSIITRKEFQEGLKIFFPRVSEFGRESILFHYMDWLDDQRAENYREALDDV
VGDYNIICPALEFTKKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLER
RVNYTKAEEILSRSIMKRWANFAKYGNPNGTQSNSTRWPVFKSTEQKYLTLNTESPKVYT
KLRAQQCRFWTLFFPKVLELTGNIDEAEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCS
DF
|
|
|
|---|
| BDBM227566 |
|---|
| n/a |
|---|
| Name | BDBM227566 |
|---|
| Synonyms: | Diethyl-3-cyano-2-methyl-1-phenylpropylphosphate (3g) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H22NO4P |
|---|
| Mol. Mass. | 311.3132 |
|---|
| SMILES | CCOP(=O)(OCC)OC(C(C)CC#N)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
