| Reaction Details |
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 | Report a problem with these data |
| Target | Androgen receptor [646-919] |
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| Ligand | BDBM227646 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| pH | 6.5±n/a |
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| Kd | 3.3e+3± 1.3e+3 nM |
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| Comments | extracted |
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| Citation |  Jehle, K; Cato, L; Neeb, A; Muhle-Goll, C; Jung, N; Smith, EW; Buzon, V; Carbó, LR; Estébanez-Perpiñá, E; Schmitz, K; Fruk, L; Luy, B; Chen, Y; Cox, MB; Bräse, S; Brown, M; Cato, AC Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif. J Biol Chem289:8839-51 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Androgen receptor [646-919] |
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| Name: | Androgen receptor [646-919] |
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| Synonyms: | ANDR_HUMAN | AR | Androgen receptor ligand-binding domain (AR-LBD) | DHTR | NR3C4 |
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| Type: | Protein |
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| Mol. Mass.: | 31698.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human AR hinge-LBD (646-919 aa) |
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| Residue: | 274 |
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| Sequence: | ASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSL
NELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYF
APDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQ
KFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKS
HMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
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| BDBM227646 |
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| n/a |
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| Name | BDBM227646 |
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| Synonyms: | Bag-1L (61-80) | RGAAAGARRPRMKKKTRRRS |
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| Type | Small organic molecule |
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| Emp. Form. | C93H176N44O23S |
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| Mol. Mass. | 2310.739 |
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| SMILES | CSCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(O)=O |r| |
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| Structure | 
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