| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase JAK3 [781-1124] |
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| Ligand | BDBM228717 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 0.55±0.55 nM |
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| Comments | extracted |
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| Citation |  Su, W; Deng, W; Li, J; Ji, J Pyrrolopyrimidine compounds and uses thereof US Patent US9346810 Publication Date 5/24/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase JAK3 [781-1124] |
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| Name: | Tyrosine-protein kinase JAK3 [781-1124] |
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| Synonyms: | JAK3 | JAK3 (aa 781-1124) | JAK3_HUMAN | Janus kinase 3 (JAK3) | Tyrosine-protein kinase JAK3 | Tyrosine-protein kinase JAK3 (781-1124) | Tyrosine-protein kinase JAK3 (aa 781-1124) |
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| Type: | n/a |
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| Mol. Mass.: | 38772.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P52333[781-1124] |
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| Residue: | 344 |
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| Sequence: | ISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESE
AHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAP
SPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS
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| BDBM228717 |
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| n/a |
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| Name | BDBM228717 |
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| Synonyms: | US10369153, Compound 64 | US9346810, 64 |
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| Type | Small Organic Molecule |
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| Emp. Form. | C14H18N6 |
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| Mol. Mass. | 270.3329 |
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| SMILES | CN(CCC#N)[C@@H]1CCN(C1)c1ncnc2[nH]ccc12 |
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| Structure | 
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