| Reaction Details |
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 | Report a problem with these data |
| Target | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase |
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| Ligand | BDBM228812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| pH | 8±n/a |
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| Kd | 2.3e+4± 2.0e+3 nM |
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| Comments | extracted |
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| Citation |  Jenkins, RJ; Heslip, KA; Meagher, JL; Stuckey, JA; Dotson, GD Structural basis for the recognition of peptide RJPXD33 by acyltransferases in lipid A biosynthesis. J Biol Chem289:15527-35 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase |
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| Name: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase |
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| Synonyms: | LPXA_ECOLI | UDP-N-acetylglucosamine acryltransferase (LpxA) | lpxA |
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| Type: | Enzyme |
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| Mol. Mass.: | 28083.70 |
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| Organism: | Escherichia coli (Enterobacteria) |
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| Description: | P0A722 |
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| Residue: | 262 |
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| Sequence: | MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDN
EIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMIN
AHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQD
VPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELA
ETYPEVKAFTDFFARSTRGLIR
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| BDBM228812 |
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| n/a |
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| Name | BDBM228812 |
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| Synonyms: | RJPXD33Δ6 | TNLYML-CONH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H56N8O9S |
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| Mol. Mass. | 752.922 |
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| SMILES | CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(N)=O |r| |
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| Structure | 
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