| Reaction Details |
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 | Report a problem with these data |
| Target | Secreted cathepsin L 1 |
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| Ligand | BDBM232218 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cathepsin L Enzyme Assay |
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| IC50 | 2.8e+3±n/a nM |
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| Citation |  Moran, BW; Anderson, FP; Ruth, DM; Fágáin, CO; Dalton, JP; Kenny, PT Fluorobenzoyl dipeptidyl derivatives as inhibitors of the Fasciola hepatica cysteine protease cathepsin L1. J Enzyme Inhib Med Chem25:1-12 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Secreted cathepsin L 1 |
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| Name: | Secreted cathepsin L 1 |
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| Synonyms: | Cathepsin L1 (CL1) | Cysteine cathepsin L endoprotease |
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| Type: | Protein |
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| Mol. Mass.: | 36773.95 |
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| Organism: | Fasciola hepatica (Liver fluke) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MRLFVLAVLTVGVLGSNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDL
GLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYV
TEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENA
YQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAA
VAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGY
IRMVRNRGNMCGIASLASLPMVARFP
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| BDBM232218 |
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| n/a |
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| Name | BDBM232218 |
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| Synonyms: | N-4-fluorobenzoyl-L-leucine-glycine nitrile (14) |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18FN3O2 |
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| Mol. Mass. | 291.3207 |
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| SMILES | CCC(C)[C@H](NC(=O)c1ccc(F)cc1)C(=O)NCC#N |r| |
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| Structure | 
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