| Reaction Details |
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 | Report a problem with these data |
| Target | Toll-like receptor 9 |
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| Ligand | BDBM232975 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TLR9 Antagonism Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 497±n/a nM |
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| Comments | extracted |
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| Citation |  Lipford, GB; Zepp, CM Immune system modulators US Patent US9353115 Publication Date 5/31/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Toll-like receptor 9 |
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| Name: | Toll-like receptor 9 |
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| Synonyms: | CD_antigen: CD289 | TLR9 | TLR9_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 115889.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NR96 |
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| Residue: | 1032 |
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| Sequence: | MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAA
PRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFL
AVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYY
KNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDL
ANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLN
ASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSF
GSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYV
DLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLS
RNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHS
FTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSL
RALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRL
RDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGF
FSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAA
VPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCG
WDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRG
RWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLE
DRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHF
YNRNFCQGPTAE
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| BDBM232975 |
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| n/a |
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| Name | BDBM232975 |
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| Synonyms: | US9353115, 63 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H34N8O2 |
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| Mol. Mass. | 466.5792 |
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| SMILES | CN1CCN(CCn2c(O)nc3c(NCCN4CCOCC4)nc(nc23)-c2ccccc2)CC1 |
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| Structure | 
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