| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] |
|---|
| Ligand | BDBM50403061 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In vitro Kinase Assay |
|---|
| pH | 8±n/a |
|---|
| IC50 | 150±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Garske, AL; Shokat, KM Methods and compositions for kinase inhibition US Patent US9353116 Publication Date 5/31/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] |
|---|
| Name: | Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] |
|---|
| Synonyms: | Proto-oncogene tyrosine-protein kinase Src (T338C) | SRC | SRC_CHICK |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 32362.46 |
|---|
| Organism: | Gallus gallus (Chicken) |
|---|
| Description: | residues 251-533 |
|---|
| Residue: | 283 |
|---|
| Sequence: | QTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQE
AQVMKKLRHEKLVQLYAVVSEEPIYIVCEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQI
ASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTA
PEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPES
LHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
|
|
|
|---|
| BDBM50403061 |
|---|
| n/a |
|---|
| Name | BDBM50403061 |
|---|
| Synonyms: | CHEMBL2216823 | US9353116, 9 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H20N6O2S |
|---|
| Mol. Mass. | 372.445 |
|---|
| SMILES | CC(C)n1nc(Cc2cccc(NS(=O)(=O)C=C)c2)c2c(N)ncnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
