| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 2J2 |
|---|
| Ligand | BDBM235143 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | CYP Inhibition Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | 6700±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Pradhan, NS; Patil, NS; Walavalkar, RR; Kulkarni, NS; Pawar, SB; Pawar, TS Aldehyde derivative of substitute oxazolidinones US Patent US9359341 Publication Date 6/7/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 2J2 |
|---|
| Name: | Cytochrome P450 2J2 |
|---|
| Synonyms: | CP2J2_HUMAN | CYP2J2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 57623.04 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P51589 |
|---|
| Residue: | 502 |
|---|
| Sequence: | MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVD
FEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHI
FKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDP
HFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFL
PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN
LICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMP
YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT
FNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLS
LKFRMGITISPVSHRLCAVPQV
|
|
|
|---|
| BDBM235143 |
|---|
| n/a |
|---|
| Name | BDBM235143 |
|---|
| Synonyms: | US9359341, Formula B |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H18ClN3O6S |
|---|
| Mol. Mass. | 463.891 |
|---|
| SMILES | Clc1ccc(s1)C(=O)N(C[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O)C=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
