| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50387556 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Reception Binding Assay |
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| Temperature | 303.15±n/a K |
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| Ki | 599.89±n/a nM |
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| IC50 | 758.03±n/a nM |
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| Comments | extracted |
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| Citation |  Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Hexahydrodibenzo[a,g]quinolizine compound, preparation method thereof, pharmaceutical composition and use thereof US Patent US9359372 Publication Date 6/7/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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|
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| BDBM50387556 |
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| n/a |
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| Name | BDBM50387556 |
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| Synonyms: | CHEMBL2057438 | US9359372, DC037077 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23NO5 |
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| Mol. Mass. | 369.411 |
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| SMILES | COc1cc(OC)c2CN3CCc4cc5OCOc5cc4[C@@H]3Cc2c1CO |r| |
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| Structure | 
|
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