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TargetCarbonic anhydrase 2
LigandBDBM50149238
Substrate/Competitor4-Nitrophenyl acetate (NPA)
Meas. Tech.Esterase Activity Assay
Ki 7.41e+3±n/a nM
Citation Kazancioglu, EA; Güney, M; Sentürk, M; Supuran, CT Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity. J Enzyme Inhib Med Chem27:880-5 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrase 2
Synonyms:CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:Enzyme
Mol. Mass.:29250.71
Organism:Homo sapiens (Human)
Description:P00918
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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BDBM50149238
4-Nitrophenyl acetate (NPA)
NameBDBM50149238
Synonyms:4-Hydroxybiphenyl | 4-Phenylphenol | 4-biphenylol | 4-diphenylol | 4-hydroxydiphenyl | Biphenyl-4-ol (8) | CHEMBL73380 | [1,1'-biphenyl]-4-ol | biphenyl-4-ol | p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphenyl | p-phenylphenol | para-hydroxydiphenyl | para-phenylphenol
TypeSmall organic molecule
Emp. Form.C12H10O
Mol. Mass.170.2072
SMILESOc1ccc(cc1)-c1ccccc1
Structure
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