| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50335803 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Bla2 Activity Assay |
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| pH | 7±n/a |
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| IC50 | 2.04e+5±n/a nM |
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| Comments | extracted |
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| Citation |  Schlesinger, SR; Bruner, B; Farmer, PJ; Kim, SK Kinetic characterization of a slow-binding inhibitor of Bla2: thiomaltol. J Enzyme Inhib Med Chem28:137-42 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | BAS3245 | Beta-lactamase (Bla2) | Beta-lactamase II | GBAA_3500 | bla2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 28177.23 |
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| Organism: | Bacillus anthracis |
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| Description: | Q93T40 |
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| Residue: | 256 |
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| Sequence: | MKNTLLKLGVCVSLLGITPFVSTISSVQAERKVEHKVIKNETGTISISQLNKNVWVHTEL
GYFNGEAVPSNGLILNTSKGLVLVDSSWDDKLTKELIEMAEKKFKKSVTDVIITHAHADR
IGGIKTLKERGIKAHSTTLTAELAKKNGYEEPLGDLQAITKLKFGNMKVETFYPGKGHTE
DNIVVWLPQYNMLVGGCLVKSASAKDLGNITDAYVNEWSTSIENVLKRYENINFVVPGHG
EVGDKGLLLHTLDLLK
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| BDBM50335803 |
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| n/a |
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| Name | BDBM50335803 |
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| Synonyms: | 3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL1650615 | Thiomaltol |
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| Type | Small organic molecule |
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| Emp. Form. | C6H6O2S |
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| Mol. Mass. | 142.176 |
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| SMILES | Cc1occc(=S)c1O |
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| Structure | 
|
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