| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 2 [1-473] |
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| Ligand | BDBM237494 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay |
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| pH | 7.5±n/a |
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| IC50 | 18±n/a nM |
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| Comments | extracted |
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| Citation |  Ren, B; Zhou, C; Wang, H Substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones US Patent US9393232 Publication Date 7/19/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Bromodomain-containing protein 2 [1-473] |
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| Name: | Bromodomain-containing protein 2 [1-473] |
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| Synonyms: | BRD2 | BRD2_HUMAN | Bromodomain-containing protein 2 (BRD2) | KIAA9001 | RING3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52271.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa 1-473 |
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| Residue: | 473 |
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| Sequence: | MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPAN
PPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQP
MDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASM
PQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNI
PHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPA
SPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKEL
LSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRL
MFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGL
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| BDBM237494 |
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| n/a |
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| Name | BDBM237494 |
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| Synonyms: | US9393232, 4.1 | US9393232, 4.1a | US9393232, 4.1b |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N2O3S |
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| Mol. Mass. | 326.37 |
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| SMILES | Cc1noc(C)c1-c1ccc2NC(=O)C(O)(c3ccsc3)c2c1 |
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| Structure | 
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