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TargetThromboxane A2 receptor
LigandBDBM238318
Substrate/Competitorn/a
Meas. Tech.FLIPR Assay
pH7.4±n/a
EC50 4832±n/a nM
Commentsextracted
Citation Donde, YNguyen, JH Therapeutic prostaglandin receptor agonists US Patent US9394273 Publication Date 7/19/2016
More Info.:Get all data from this article,  Assay Method
 
Thromboxane A2 receptor
Name:Thromboxane A2 receptor
Synonyms:Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:Enyzme
Mol. Mass.:37445.28
Organism:Homo sapiens (Human)
Description:P21731
Residue:343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM238318
n/a
NameBDBM238318
Synonyms:US9394273, 7
TypeSmall organic molecule
Emp. Form.C24H25ClO4
Mol. Mass.412.906
SMILESOC(Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r|
Structure
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