Reaction Details |
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Target | Thromboxane A2 receptor |
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Ligand | BDBM238334 |
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Substrate/Competitor | n/a |
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Meas. Tech. | FLIPR Assay |
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pH | 7.4±n/a |
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EC50 | 2446±n/a nM |
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Comments | extracted |
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Citation | Donde, Y; Nguyen, JH Therapeutic prostaglandin receptor agonists US Patent US9394273 Publication Date 7/19/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Thromboxane A2 receptor |
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Name: | Thromboxane A2 receptor |
Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
Type: | Enyzme |
Mol. Mass.: | 37445.28 |
Organism: | Homo sapiens (Human) |
Description: | P21731 |
Residue: | 343 |
Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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BDBM238334 |
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n/a |
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Name | BDBM238334 |
Synonyms: | US9394273, 23 | US9394273, 24 |
Type | Small organic molecule |
Emp. Form. | C24H24F2O4 |
Mol. Mass. | 414.4418 |
SMILES | OC(Cc1ccc(F)c(F)c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O |r| |
Structure |
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