| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM103754 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cAMP Assay |
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| Temperature | 310.15±n/a K |
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| EC50 | 1±n/a nM |
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| Comments | extracted |
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| Citation |  Hughes, AD; Byun, D; Jacobsen, JR Diamide compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity US Patent US9394275 Publication Date 7/19/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM103754 |
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| n/a |
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| Name | BDBM103754 |
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| Synonyms: | US8551978, I-22 | US8816088, I-22 | US9394275, I-22 | US9572802, Compound I-22 | US9682957, I-22 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H58N6O7 |
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| Mol. Mass. | 831.0101 |
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| SMILES | CC(Cc1cccc(CC(=O)NCCCCN(C)C(=O)CCN2CCC(CC2)OC(=O)Nc2ccccc2-c2ccccc2)c1)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12 |r| |
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| Structure | 
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