| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein [1027-1207,C159S] |
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| Ligand | BDBM241940 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET Assay |
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| pH | 7.5±n/a |
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| IC50 | >3000±n/a nM |
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| Comments | extracted |
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| Citation |  Niu, D; Petter, RC; Qiao, L; Singh, J HCV protease inhibitors and uses thereof US Patent US9422333 Publication Date 8/23/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein [1027-1207,C159S] |
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| Name: | Genome polyprotein [1027-1207,C159S] |
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| Synonyms: | POLG_HCV1 | Protease NS3/Non-structural protein 4A (NS3/NS4A) (C159S) |
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| Type: | Enzyme |
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| Mol. Mass.: | 19105.23 |
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| Organism: | Hepatitis C virus genotype 1b (isolate Con1) (HCV) |
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| Description: | P26664[1027-1207,C159S] |
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| Residue: | 181 |
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| Sequence: | APITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAG
TRTIASPKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRG
DSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGLFRAAVSTRGVAKAVDFIPVENLETTMR
S
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| BDBM241940 |
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| n/a |
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| Name | BDBM241940 |
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| Synonyms: | US9422333, I-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H42N6O6 |
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| Mol. Mass. | 546.659 |
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| SMILES | CC(C)(C)NC(=O)N[C@@H](CNC(=O)C=C)C(=O)N1CC2[C@@H]([C@H]1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(C)C |r,w:25.26| |
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| Structure | 
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