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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase Lyn | ||
| Ligand | BDBM243041 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | In Vitor Src Tyrosine Kinase Activity Assay | ||
| Temperature | 295.15±0 K | ||
| IC50 | 0.3±0.0 nM | ||
| Citation |  Dincer, S; Cetin, KT; Onay-Besikci, A; Ölgen, S Synthesis, biological evaluation and docking studies of new pyrrolo[2,3-d] pyrimidine derivatives as Src family-selective tyrosine kinase inhibitors. J Enzyme Inhib Med Chem28:1080-7 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase Lyn | |||
| Name: | Tyrosine-protein kinase Lyn | ||
| Synonyms: | JTK8 | LYN | LYN_HUMAN | Lck/Yes-related novel protein tyrosine kinase | Tyrosine-protein kinase Lyn (LYN) | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog | p53Lyn | p56Lyn | ||
| Type: | Protein | ||
| Mol. Mass.: | 58575.92 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P07948 | ||
| Residue: | 512 | ||
| Sequence: |
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| BDBM243041 | |||
| n/a | |||
| Name | BDBM243041 | ||
| Synonyms: | A-419259 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H34N6O | ||
| Mol. Mass. | 482.6199 | ||
| SMILES | CN1CCN(CC1)[C@H]1CCC(CC1)n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r,wD:7.7,(26.44,-17.33,;25.67,-18.66,;25.16,-19.93,;25.3,-21.48,;23.96,-22.25,;24.33,-20.97,;24.33,-19.43,;22.48,-22.65,;22.48,-21.11,;21.14,-20.34,;19.81,-21.11,;19.81,-22.65,;21.14,-23.42,;18.32,-20.71,;19.23,-19.47,;18.32,-18.22,;18.8,-16.76,;20.3,-16.44,;20.78,-14.97,;19.75,-13.83,;20.22,-12.36,;21.73,-12.04,;22.76,-13.19,;24.27,-12.87,;24.74,-11.4,;23.71,-10.26,;22.21,-10.58,;18.24,-14.15,;17.77,-15.61,;16.86,-18.7,;15.52,-17.93,;15.52,-16.39,;14.19,-18.7,;14.19,-20.24,;15.52,-21.01,;16.86,-20.24,)| | ||
| Structure | 
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