| Reaction Details |
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 | Report a problem with these data |
| Target | Serum paraoxonase/arylesterase 1 |
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| Ligand | BDBM243048 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Activity Assay |
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| IC50 | 7.01e+5±n/a nM |
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| Citation |  Akbaba, Y; Türkes, C; Polat, L; Söyüt, H; Sahin, E; Menzek, A; Göksu, S; Beydemir, S Synthesis and paroxonase activities of novel bromophenols. J Enzyme Inhib Med Chem28:1073-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serum paraoxonase/arylesterase 1 |
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| Name: | Serum paraoxonase/arylesterase 1 |
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| Synonyms: | A-esterase 1 | Aromatic esterase 1 | K-45 | PON | PON 1 | PON1 | PON1_HUMAN | Paraoxonase (PON1) | Paraoxonase (hPON1) | Paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Serum paraoxonase 1 (PON1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39719.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27169 |
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| Residue: | 355 |
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| Sequence: | MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
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| BDBM243048 |
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| n/a |
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| Name | BDBM243048 |
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| Synonyms: | (3-Bromo-4,5-dihydroxyphenyl)(2,3-dibromo-5,6-dihydroxyphenyl)methanone (12) |
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| Type | Small organic molecule |
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| Emp. Form. | C13H7Br3O5 |
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| Mol. Mass. | 482.904 |
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| SMILES | Oc1cc(Br)c(Br)c(C(=O)c2cc(O)c(O)c(Br)c2)c1O |
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| Structure | 
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