Reaction Details | |||
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Target | Alpha-glucosidase MAL12 | ||
Ligand | BDBM23406 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
pH | 7±n/a | ||
IC50 | 2.753e+5±n/a nM | ||
Comments | extracted | ||
Citation | Yousefi, R; Alavian-Mehr, MM; Mokhtari, F; Panahi, F; Mehraban, MH; Khalafi-Nezhad, A Pyrimidine-fused heterocycle derivatives as a novel class of inhibitors for a-glucosidase. J Enzyme Inhib Med Chem28:1228-35 (2013) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Alpha-glucosidase MAL12 | |||
Name: | Alpha-glucosidase MAL12 | ||
Synonyms: | α-Glucosidase | MAL12 | MAL12_YEAST | MAL1S | Maltase | alpha-Glucosidase (α-Glucosidase) | ||
Type: | Protein | ||
Mol. Mass.: | 68084.32 | ||
Organism: | Saccharomyces cerevisiae | ||
Description: | P53341 | ||
Residue: | 584 | ||
Sequence: |
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BDBM23406 | |||
n/a | |||
Name | BDBM23406 | ||
Synonyms: | (3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol | Acarbose | US11292789, Acarbose | ||
Type | Carbohydrate | ||
Emp. Form. | C25H43NO18 | ||
Mol. Mass. | 645.6048 | ||
SMILES | C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:37| | ||
Structure |