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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine-protein kinase ATM | ||
| Ligand | BDBM245505 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Cellular Assay | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 0.2±n/a nM | ||
| Comments | extracted | ||
| Citation |  Barlaam, BC; Pike, KG Imidazo[4,5-c]quinolin-2-one compounds and their use in treating Cancer US Patent US9428503 Publication Date 8/30/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine-protein kinase ATM | |||
| Name: | Serine-protein kinase ATM | ||
| Synonyms: | A-T mutated | ATM | ATM_HUMAN | Ataxia telangiectasia mutated | ||
| Type: | Protein | ||
| Mol. Mass.: | 350696.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q13315 | ||
| Residue: | 3056 | ||
| Sequence: |
| ||
| BDBM245505 | |||
| n/a | |||
| Name | BDBM245505 | ||
| Synonyms: | US9428503, 33 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H35N5O3 | ||
| Mol. Mass. | 501.6199 | ||
| SMILES | CO[C@H]1C[C@H](C1)n1c2c(cnc3ccc(cc23)-c2ccc(OCCCN3CCCCC3)nc2)n(C)c1=O |r,wD:4.6,2.1,(3.76,4.9,;3.37,3.41,;4.45,2.32,;4.45,.78,;5.99,.78,;5.99,2.32,;7.08,-.31,;6.76,-1.82,;8.1,-2.59,;8.1,-4.13,;6.76,-4.9,;5.43,-4.13,;4.1,-4.9,;2.76,-4.13,;2.76,-2.59,;4.1,-1.82,;5.43,-2.59,;1.43,-1.82,;1.43,-.28,;.09,.49,;-1.24,-.28,;-2.57,.49,;-3.91,-.28,;-5.24,.49,;-6.57,-.28,;-7.91,.49,;-7.91,2.03,;-9.24,2.8,;-10.57,2.03,;-10.57,.49,;-9.24,-.28,;-1.24,-1.82,;.09,-2.59,;9.24,-1.56,;10.57,-2.33,;8.61,-.15,;9.38,1.19,)| | ||
| Structure | 
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