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TargetGenome polyprotein [1973-2419,Y2165H]
LigandBDBM245928
Substrate/Competitorn/a
Meas. Tech.Transient Transfection Assay
EC50 275±n/a nM
Citation Vandyck, KLast, SJHoupis, INRaboisson, PJ Benzimidazole-imidazole derivatives US Patent US9433609 Publication Date 9/6/2016
More Info.:Get all data from this article,  Assay Method
 
Genome polyprotein [1973-2419,Y2165H]
Name:Genome polyprotein [1973-2419,Y2165H]
Synonyms:Non-structural protein 5A (NS5A)(Y93H) | POLG_HCVCO | Serine protease NS5A (Y93H)
Type:Enzyme
Mol. Mass.:48680.14
Organism:Hepatitis C virus genotype 1b (isolate Con1) (HCV)
Description:aa 1973-2419
Residue:447
Sequence:
SGSWLRDVWDWICTVLTDFKTWLQSKLLPRLPGVPFFSCQRGYKGVWRGDGIMQTTCPCG
AQITGHVKNGSMRIVGPRTCSNTWHGTFPINAHTTGPCTPSPAPNYSRALWRVAAEEYVE
VTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREEVTFLVGLN
QYLVGSQLPCEPEPDVAVLTSMLTDPSHITAETAKRRLARGSPPSLASSSASQLSAPSLK
ATCTTRHDSPDADLIEANLLWRQEMGGNITRVESENKVVILDSFEPLQAEEDEREVSVPA
EILRRSRKFPRAMPIWARPDYNPPLLESWKDPDYVPPVVHGCPLPPAKAPPIPPPRRKRT
VVLSESTVSSALAELATKTFGSSESSAVDSGTATASPDQPSDDGDAGSDVESYSSMPPLE
GEPGDPDLSDGSWSTVSEEASEDVVCC
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  Blast E-value cutoff:
BDBM245928
n/a
NameBDBM245928
Synonyms:US9433609, 21
TypeSmall organic molecule
Emp. Form.C43H52N8O7
Mol. Mass.792.9224
SMILESCC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2[nH]c(nc2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC |r|
Structure
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