| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase D2 |
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| Ligand | BDBM87245 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Activity Assay |
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| IC50 | 240±n/a nM |
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| Citation |  Lindsley, CW; Brown, AH Antiviral therapies with phospholipase D inhibitors US Patent US9453017 Publication Date 9/27/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase D2 |
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| Name: | Phospholipase D2 |
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| Synonyms: | PLD2 | PLD2_HUMAN | Phospholipase D2 | Phospholipase D2 (PLD2) | phospholipase D2 isoform PLD2A |
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| Type: | Protein |
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| Mol. Mass.: | 106002.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 933 |
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| Sequence: | MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFA
PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVL
MSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYR
NYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV
KDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQAR
WWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIF
ITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRAL
MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSE
SAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW
RDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQ
CTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDE
IVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR
LKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLL
GKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICD
DFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQ
GHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
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| BDBM87245 |
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| n/a |
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| Name | BDBM87245 |
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| Synonyms: | CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide, 56 | N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthamide (Inh_VU0155056) | N-[2-[4-(2-keto-3H-benzimidazol-1-yl)piperidino]ethyl]-2-naphthamide;hydrochloride | N-[2-[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide;hydrochloride | N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide;hydrochloride | N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide;hydrochloride | US9453017, 3 | VU0155056-2 | VU0156056 (1) | cid_53481919 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H26N4O2 |
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| Mol. Mass. | 414.4995 |
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| SMILES | O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc2ccccc2c1 |
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| Structure | 
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