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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Ligand | BDBM253997 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assays (DELFIA) | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 1±n/a nM | ||
| Comments | extracted | ||
| Citation |  Reiser, U 6-alkynyl-pyridine derivatives US Patent US9481673 Publication Date 11/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Baculoviral IAP repeat-containing protein 2 [256-363] | |||
| Name: | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Cellular inhibitor of apoptosis 1 (c-IAP1/BIR3) | Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3) | IAP repeat-containing protein 2 (cIAP1) BIR-3 | MIHB | RNF48 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 12600.71 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Human cIAP BIR3 domain (256-363 aa) | ||
| Residue: | 108 | ||
| Sequence: |
| ||
| BDBM253997 | |||
| n/a | |||
| Name | BDBM253997 | ||
| Synonyms: | US9481673, (S)-7 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H30N8O | ||
| Mol. Mass. | 566.655 | ||
| SMILES | CN[C@@H](C)C(=O)Nc1ccc(-c2c(nc3cc(C)ccn23)-c2cnc(C)nc2)c(n1)C#Cc1ccc2c(C)nccc2c1 |r,wU:2.2,(-6,-4.1,;-7.34,-3.33,;-7.34,-1.79,;-8.67,-1.02,;-6,-1.02,;-6,.52,;-4.67,-1.79,;-3.33,-1.02,;-3.33,.52,;-2,1.29,;-.67,.52,;.67,1.29,;.67,2.83,;2.13,3.3,;3.04,2.06,;4.57,1.9,;5.19,.49,;6.68,.09,;4.29,-.76,;2.76,-.6,;2.13,.81,;-.42,3.92,;-.02,5.4,;-1.11,6.49,;-2.6,6.09,;-3.69,7.18,;-3,4.61,;-1.91,3.52,;-.67,-1.02,;-2,-1.79,;.67,-1.79,;2,-2.56,;3.33,-3.33,;3.33,-4.87,;4.67,-5.64,;6,-4.87,;7.34,-5.64,;7.34,-7.18,;8.67,-4.87,;8.67,-3.33,;7.34,-2.56,;6,-3.33,;4.67,-2.56,)| | ||
| Structure | 
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