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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Non-receptor tyrosine-protein kinase TYK2 | ||
| Ligand | BDBM255023 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Assay | ||
| IC50 | 190±n/a nM | ||
| Citation |  Takahashi, K; Watanabe, T; Hayashi, K; Kurihara, K; Nakamura, T; Yamamoto, A; Nishimura, T; Kamiyama, T; Hidaka, Y Tricyclic pyrrolopyridine compound, and JAK inhibitor US Patent US9475813 Publication Date 10/25/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Non-receptor tyrosine-protein kinase TYK2 | |||
| Name: | Non-receptor tyrosine-protein kinase TYK2 | ||
| Synonyms: | Non-receptor tyrosine-protein kinase TYK2 (TYK2) | TYK2 | TYK2_HUMAN | Tyrosine-protein kinase TYK2 | ||
| Type: | Protein | ||
| Mol. Mass.: | 133666.03 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29597 | ||
| Residue: | 1187 | ||
| Sequence: |
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| BDBM255023 | |||
| n/a | |||
| Name | BDBM255023 | ||
| Synonyms: | US9475813, 28 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H26F3N5O | ||
| Mol. Mass. | 421.4592 | ||
| SMILES | FC(F)(F)CNC[C@H]1CC[C@@H](CC1)N1CN(C2CC2)C(=O)c2cnc3[nH]ccc3c12 |r,wU:10.13,wD:7.6,(-.87,9.06,;.67,9.01,;.71,10.55,;.62,7.47,;2.21,8.96,;2.93,7.6,;4.47,7.56,;5.2,6.2,;4.39,4.89,;5.12,3.53,;6.66,3.48,;7.47,4.79,;6.74,6.15,;7.38,2.13,;8.92,2.08,;9.65,.72,;11.19,.67,;12.55,1.4,;12.5,-.14,;8.84,-.59,;9.57,-1.94,;7.3,-.54,;6.49,-1.85,;4.95,-1.8,;4.22,-.44,;2.73,-.08,;2.61,1.46,;4.04,2.04,;5.03,.87,;6.57,.82,)| | ||
| Structure | 
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