| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM259991 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cAMP Assay |
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| Temperature | 310.15±n/a K |
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| EC50 | 42.5±n/a nM |
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| Comments | extracted |
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| Citation |  Grether, U; Kimbara, A; Matthias, N; Fabienne, R; Stephan, R; Rogers-Evans, M; Schulz-Gasch, T Pyrazole compounds as CB2 agonists US Patent US9512132 Publication Date 12/6/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM259991 |
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| n/a |
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| Name | BDBM259991 |
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| Synonyms: | US9512132, 27 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18F2N6O |
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| Mol. Mass. | 360.3612 |
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| SMILES | Cc1nonc1Cn1ncc2c(nc(cc12)C1CC1)N1CCC(F)(F)C1 |
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| Structure | 
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