| Reaction Details |
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 | Report a problem with these data |
| Target | Epoxide hydrolase 1 |
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| Ligand | BDBM25744 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 480±n/a nM |
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| Citation |  Guedes, AG; Hammock, BD; Morisseau, C Treatment of inflammatory disorders in non-human mammals US Patent US10383835 Publication Date 8/20/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Epoxide hydrolase 1 |
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| Name: | Epoxide hydrolase 1 |
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| Synonyms: | EPHX1 |
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| Type: | n/a |
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| Mol. Mass.: | 55532.32 |
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| Organism: | Felis catus (Cat) (Felis silvestris catus) |
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| Description: | A0A2I2V3F9 |
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| Residue: | 483 |
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| Sequence: | MLTSPSFSLGVTATMVPTVPSTCPRLLKGKGIMWLEILLASVLAFVVYWFVSRDKEETLP
LEDGWWGPGARPTAPEDESIRPFKVETSDEEIKDLHRRIDGTRLTPPLEDSRFHYGFNSN
YLKKILSYWRNEFDWRKQVEMLNRYPHFKTRIEGLDIHFVHVKPPQLPPGRTPKPLLMVH
GWPGSFYEFYKIIPLLTDPANHGLSEEHVFEVICPSIPGYAFSEAASKKGLNSVATARIF
YKLMLRLGFREFYIQGGDWGALICTHMAQMVPSHVKGLHLNMAFILNGRILTLFLVRHCP
RLFGFTQRDMELMLPFKEKIFYKPLRESGYMHIQSTKPDTVGCALNDSPAGLAAYILEKF
STWTDSEFQELEDGGLERKFSLDDLLTNVMLYWTTGTITSSQRFYKENRGQLFKQDRVKV
SVPTGLAAFPCELMHIPERWVKGKYPRLVSYSYMPRGGHFAALEEPELLARDIRKFVGLL
ELP
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| BDBM25744 |
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| n/a |
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| Name | BDBM25744 |
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| Synonyms: | 3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)phenyl]urea | US10383835, Compound 1555 | US8501783, 1555 | Urea-based compound, 25 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18F3N3O3 |
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| Mol. Mass. | 345.3169 |
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| SMILES | CC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 |
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| Structure | 
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