| Reaction Details |
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 | Report a problem with these data |
| Target | Epoxide hydrolase |
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| Ligand | BDBM50327809 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 44.0±n/a nM |
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| Citation |  Guedes, AG; Hammock, BD; Morisseau, C Treatment of inflammatory disorders in non-human mammals US Patent US10383835 Publication Date 8/20/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Epoxide hydrolase |
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| Name: | Epoxide hydrolase |
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| Synonyms: | EPHX1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52112.47 |
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| Organism: | Ovis aries (Sheep) |
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| Description: | W5Q7Q6 |
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| Residue: | 451 |
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| Sequence: | MWLEILLASVLGFVIYWFVSKDKEETLPLEDGWWGPGVRPTAGEDKSIRPFKVETSDEEI
NDLHQRIDRVRLTPPLEDSRFHYGFNSNYLKKIISYWRNEFDWRKQVEILNKYPHFKTKI
EGLDIHFIHVKPPNLPSGQTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV
ICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQKFYIQGGDWGALICTNMAQLVP
SHIKGLHLNMALILRNFYTLTLPLGRCFGGLFGYTERDMELIYPFKKIFFSLLRESGYMH
IQSTKPDTVGCALNDSPVGLAAYILEKFSTWTNSEFRDLEDGGLERKFSLDDLLTGIMLY
WTTGTITSSQRFYKENLAQVNKHETLKVYVPTGFAAFPCELIHSPEKWVKTKYPKLISYS
YMPRGGHFAAFEEPELLAQDIRKFVGLQERQ
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| BDBM50327809 |
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| n/a |
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| Name | BDBM50327809 |
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| Synonyms: | 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea | CHEMBL1258904 | US10383835, Compound 1770 | US11123311, Compound 1770 | US9296693, 40 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20F3N3O3 |
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| Mol. Mass. | 359.3435 |
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| SMILES | CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 |
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| Structure | 
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