| Reaction Details |
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 | Report a problem with these data |
| Target | Metalloproteinase inhibitor 2 |
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| Ligand | BDBM413584 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | <1.000±n/a nM |
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| Citation |  Prades Cosano, R; Seco Moral, J; Tarragó Clua, MT Gelatinase inhibitors and use thereof US Patent US10414797 Publication Date 9/17/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Metalloproteinase inhibitor 2 |
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| Name: | Metalloproteinase inhibitor 2 |
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| Synonyms: | Metalloproteinase inhibitor 2 (TIMP2) | TIMP-2 | TIMP2 | TIMP2_CRILO | Tissue inhibitor of metalloproteinases 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21943.02 |
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| Organism: | Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster) |
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| Description: | Q60453 |
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| Residue: | 196 |
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| Sequence: | RACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDK
DIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSL
NHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWY
RGAAPPKQEFLDIEDP
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| BDBM413584 |
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| n/a |
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| Name | BDBM413584 |
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| Synonyms: | (2S,4R)—N-[(1S)-1-[[(1S)-3-benzamido-1-(hydroxycarbamoyl)propyl]carbamoyl]-2-methyl-butyl]-4-fluoro-N-methyl-1-hexanoyl-pyrrolidine-2-carboxamide | US10414797, Example 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H44FN5O6 |
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| Mol. Mass. | 577.688 |
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| SMILES | CCCCCC(=O)N1C[C@H](F)C[C@H]1C(=O)N(C)[C@@H](C(C)CC)C(=O)N[C@@H](CCNC(=O)c1ccccc1)C(=O)NO |r| |
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| Structure | 
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