| Reaction Details |
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 | Report a problem with these data |
| Target | Vesicular acetylcholine transporter |
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| Ligand | BDBM70577 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Affinity Assay |
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| Ki | 5.40±0.6 nM |
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| Citation |  Tu, Z; Luo, Z; Liu, H; Jin, H; Parsons, SM Sulfur-containing compounds targeting vesicular acetylcholine transporter US Patent US10421722 Publication Date 9/24/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Vesicular acetylcholine transporter |
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| Name: | Vesicular acetylcholine transporter |
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| Synonyms: | SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56900.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507628 |
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| Residue: | 532 |
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| Sequence: | MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
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| BDBM70577 |
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| n/a |
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| Name | BDBM70577 |
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| Synonyms: | US10421722, Compound 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27NO4S |
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| Mol. Mass. | 413.53 |
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| SMILES | CS(=O)(=O)c1ccc(cc1)C(=O)C1CCN(CC1)[C@@H]1Cc2ccccc2C[C@H]1O |r| |
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| Structure | 
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