| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vesicular acetylcholine transporter |
|---|
| Ligand | BDBM413594 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Affinity Assay |
|---|
| Ki | 2.40±0.3 nM |
|---|
| Citation |  Tu, Z; Luo, Z; Liu, H; Jin, H; Parsons, SM Sulfur-containing compounds targeting vesicular acetylcholine transporter US Patent US10421722 Publication Date 9/24/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vesicular acetylcholine transporter |
|---|
| Name: | Vesicular acetylcholine transporter |
|---|
| Synonyms: | SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56900.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1507628 |
|---|
| Residue: | 532 |
|---|
| Sequence: | MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
|
|
|
|---|
| BDBM413594 |
|---|
| n/a |
|---|
| Name | BDBM413594 |
|---|
| Synonyms: | US10421722, Compound 3 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H27NO2S |
|---|
| Mol. Mass. | 381.531 |
|---|
| SMILES | CSc1ccc(cc1)C(=O)C1CCN(CC1)[C@@H]1Cc2ccccc2C[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
