| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine 5'-monophosphoramidase HINT1 |
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| Ligand | BDBM426059 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Isothermal Titration Calorimetry (ITC) |
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| Kd | 920±70 nM |
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| Citation |  Wagner, CR; Shah, R Sulfamide and sulfamate inhibitors of hHint1 US Patent US10513520 Publication Date 12/24/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine 5'-monophosphoramidase HINT1 |
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| Name: | Adenosine 5'-monophosphoramidase HINT1 |
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| Synonyms: | Adenosine 5'-monophosphoramidase | HINT | HINT1 | HINT1_HUMAN | Histidine triad nucleotide-binding protein 1 | PKCI-1 | PKCI1 | PRKCNH1 | Protein kinase C inhibitor 1 | Protein kinase C-interacting protein 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 13803.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_795618 |
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| Residue: | 126 |
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| Sequence: | MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI
SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ
MHWPPG
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| BDBM426059 |
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| n/a |
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| Name | BDBM426059 |
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| Synonyms: | US10513520, Compound 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N8O7S |
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| Mol. Mass. | 532.53 |
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| SMILES | Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CNS(=O)(=O)NC(=O)CCc2c[nH]c3ccccc23)C(O)[C@@H]1O |r| |
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| Structure | 
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