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TargetProcathepsin L
LigandBDBM429284
Substrate/Competitorn/a
Meas. Tech.No assay is provided
EC50 193±n/a nM
Citation Pillaiyar, TWendt, LLManickam, MEaswaran, M The recent outbreaks of human coronaviruses: A medicinal chemistry perspective. Med Res Rev0:0 (2020) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Procathepsin L
Name:Procathepsin L
Synonyms:CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:Enzyme
Mol. Mass.:37557.19
Organism:Homo sapiens (Human)
Description:Purchased from Calbiochem (San Diego, CA).
Residue:333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM429284
n/a
NameBDBM429284
Synonyms:med.21724, Compound 22
TypeSmall Organic Molecule
Emp. Form.C28H33N5O6
Mol. Mass.535.5915
SMILESCC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NNC(=O)OCC(=O)N1CCCc2ccccc12
Structure
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