| Reaction Details |
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 | Report a problem with these data |
| Target | UL37 immediate early glycoprotein |
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| Ligand | BDBM435735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | The inhibition of HCMV replication by digitoxin |
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| EC50 | 322±11.67 nM |
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| Citation |  Boger, R Cardiac glycoside analogs and their use in methods for inhibition of viral infection US Patent US10610539 Publication Date 4/7/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| UL37 immediate early glycoprotein |
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| Name: | UL37 immediate early glycoprotein |
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| Synonyms: | UL37 | VGLI_HCMVA |
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| Type: | Protein |
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| Mol. Mass.: | 56144.76 |
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| Organism: | HHV-5 |
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| Description: | P16778 |
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| Residue: | 487 |
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| Sequence: | MSPVYVNLLGSVGLLAFWYFSYRWIQRKRLEDPLPPWLRKKKACALTRRSRHRLRRQHGV
IDGENSETERSVDLVAALLAEAGEESVTEDTEREDTEEEREDEEEENEARTPEVNPIDAE
GLSGLAREACEALKKALRRHRFLWQRRQRARMLQHNGPQQSHHAAVFCRVHGLRGFQVSV
WLLLTLLWSTGHGVSVRCTYHGTDVNRTSNTTSMNCHLNCTRNHTQIYNGPCLGTEARLP
LNVTFNQSRRKWHSVMLKFGFQYHLEGWFPLRVLNESREINVTEVHGEVACFRNDTNVTV
GQLTLNFTGHSYVLRAIAHTSPFESYVRWEETNVTDNATSSENTTTVMSTLTKYAESDYI
FLQDMCPRFLKRTVKLTRNKTKHNVTVTGNNMTTLPVWTPECKGWTYWTTLSVMWRNRRS
ALLRAKSRALGHWALLSICTVAAGSIALLSLFCILLIGLRRDLLEDFRYICRDEGSSSTK
NDVHRIV
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| BDBM435735 |
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| n/a |
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| Name | BDBM435735 |
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| Synonyms: | US10610539, Compound Tris-D-rhamnose |
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| Type | Small organic molecule |
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| Emp. Form. | C61H98O24 |
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| Mol. Mass. | 1215.4164 |
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| SMILES | CC1OC(CC(OC2OC(C)[C@@H](OC3OC(C)[C@H](OC4OC(C)[C@H](O)C(O)[C@H]4O)C(O)[C@H]3O)C(O)[C@H]2O)C1C)OC1C(C)OC(OC2C(O)CC(O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4CC[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)OC2C)C(C)C1O |r,t:78| |
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| Structure | 
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