| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Chymotrypsin-like protease CTRL-1 |
|---|
| Ligand | BDBM441784 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Proteasome-Activity Inhibitory Assay |
|---|
| IC50 | 7.41±n/a nM |
|---|
| Citation |  Yang, J; Cen, JJ; Fan, XM Epoxyketone compounds for enzyme inhibition US Patent US10640533 Publication Date 5/5/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Chymotrypsin-like protease CTRL-1 |
|---|
| Name: | Chymotrypsin-like protease CTRL-1 |
|---|
| Synonyms: | CTRL | CTRL1 | CTRL_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28008.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_49606 |
|---|
| Residue: | 264 |
|---|
| Sequence: | MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC
GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN
DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP
LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN
VRAPAVYTRVSKFSTWINQVIAYN
|
|
|
|---|
| BDBM441784 |
|---|
| n/a |
|---|
| Name | BDBM441784 |
|---|
| Synonyms: | US10640533, Identification number CX13-600 | US10640533, Table 1.31 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C37H47N5O7 |
|---|
| Mol. Mass. | 673.7984 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)c1cc(CN2CCOCC2)on1)C(=O)[C@@]1(C)CO1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
