| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsin-like protease CTRL-1 |
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| Ligand | BDBM441788 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Proteasome-Activity Inhibitory Assay |
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| IC50 | 59.3±n/a nM |
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| Citation |  Yang, J; Cen, JJ; Fan, XM Epoxyketone compounds for enzyme inhibition US Patent US10640533 Publication Date 5/5/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Chymotrypsin-like protease CTRL-1 |
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| Name: | Chymotrypsin-like protease CTRL-1 |
|---|
| Synonyms: | CTRL | CTRL1 | CTRL_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28008.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_49606 |
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| Residue: | 264 |
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| Sequence: | MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFC
GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNN
DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALP
LVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCN
VRAPAVYTRVSKFSTWINQVIAYN
|
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|
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| BDBM441788 |
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| n/a |
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| Name | BDBM441788 |
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| Synonyms: | US10640533, Identification number CX13-606 | US10640533, Table 1.35 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H50N4O7 |
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| Mol. Mass. | 650.8048 |
|---|
| SMILES | COC[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)Cc1ccc(CN2CCOCC2)cc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| |
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| Structure | 
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