| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform C of Bromodomain-containing protein 4 (Short) |
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| Ligand | BDBM298351 |
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| Substrate/Competitor | n/a |
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| Kd | 2100±n/a nM |
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| Citation |  Landau, SB; Kagey, M Bromodomain inhibitors US Patent US10124009 Publication Date 11/13/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform C of Bromodomain-containing protein 4 (Short) |
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| Name: | Isoform C of Bromodomain-containing protein 4 (Short) |
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| Synonyms: | BET bromodomain 4 (BRD4) | BRD4 | BRD4_HUMAN | Bromodomain-containing protein 4 (Short) | HUNK1 |
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| Type: | n/a |
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| Mol. Mass.: | 80477.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60885-2 |
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| Residue: | 722 |
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| Sequence: | MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV
APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE
KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE
SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK
PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETG
PA
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| BDBM298351 |
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| n/a |
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| Name | BDBM298351 |
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| Synonyms: | US10124009, Compound 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21Br2ClN4O3S |
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| Mol. Mass. | 628.764 |
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| SMILES | Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)OC\C(Br)=C(/Br)CO)c1nnc(C)n-21)c1ccc(Cl)cc1 |r,c:8| |
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| Structure | 
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