| Reaction Details |
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 | Report a problem with these data |
| Target | POU domain, class 2, transcription factor 2 |
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| Ligand | BDBM330044 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 10000±n/a nM |
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| Citation |  Bacon, EM; Cai, ZR; Chen, X; Cottell, JJ; Desai, MC; Ji, M; Jin, H; Lazerwith, SE; Mish, MR; Morganelli, PA; Pyun, H; Taylor, JG; Trejo Martin, TA Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections US Patent US10689399 Publication Date 6/23/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| POU domain, class 2, transcription factor 2 |
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| Name: | POU domain, class 2, transcription factor 2 |
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| Synonyms: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 | OCT2 | OCT2 | OTF-2 | OTF2 | Oct-2 | Octamer-binding protein 2 | Octamer-binding transcription factor 2 | Octamer-binding transcription factor 2 (OCT2) | PO2F2_HUMAN | POU domain, class 2, transcription factor 2 | POU2F2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51217.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109671 |
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| Residue: | 479 |
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| Sequence: | MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPS
TKIKAEDPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHL
QPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLS
HPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTT
ISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKK
RTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSA
APMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGG
GGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP
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| BDBM330044 |
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| n/a |
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| Name | BDBM330044 |
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| Synonyms: | (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-trifluoroethyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2, 1-b][1,3]oxazepine-10-carboxamide | US10689399, Compound 36 | US11548901, Compound 36 | US9663528, 36 | US9732092, Compound 36 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18F5N3O5 |
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| Mol. Mass. | 499.3874 |
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| SMILES | Oc1c2C(=O)N3[C@@H]4CC[C@@H](C4)OC3Cn2cc(C(=O)N[C@@H](c2ccc(F)cc2F)C(F)(F)F)c1=O |THB:13:12:8.7:10,3:5:8.7:10| |
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| Structure | 
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