Reaction Details |
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Target | Protein S100-A9 |
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Ligand | BDBM299088 |
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Substrate/Competitor | n/a |
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Meas. Tech. | S100A9-RAGE inhibition assay |
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IC50 | >1000±n/a nM |
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Citation | Fritzson, I; Liberg, D; East, S; Mackinnon, C; Prevost, N N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors US Patent US10125125 Publication Date 11/13/2018 |
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More Info.: | Get all data from this article, Assay Method |
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Protein S100-A9 |
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Name: | Protein S100-A9 |
Synonyms: | CAGB | CFAG | Calgranulin-B | Calprotectin L1H subunit | Leukocyte L1 complex heavy chain | MRP-14 | MRP14 | Migration inhibitory factor-related protein 14 | S100 calcium-binding protein A9 | S100A9 | S10A9_HUMAN | p14 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 13239.84 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 114 |
Sequence: | MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
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BDBM299088 |
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n/a |
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Name | BDBM299088 |
Synonyms: | N-(5-chloro-3-hydroxypyridin-2-yl)-6-(dimethylamino)-5-methanesulfonylpyridine-3-sulfonamide | US10125125, Example 136 |
Type | Small organic molecule |
Emp. Form. | C13H15ClN4O5S2 |
Mol. Mass. | 406.865 |
SMILES | CN(C)c1ncc(cc1S(C)(=O)=O)S(=O)(=O)Nc1ncc(Cl)cc1O |
Structure |
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