| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 26 |
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| Ligand | BDBM451739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| IC50 | >1000±n/a nM |
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| Citation |  Gray, NS; Buhrlage, S; Anderson, K; Cottini, F; Tonon, G STK4 inhibitors for treatment of hematologic malignancies US Patent US10710978 Publication Date 7/14/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 26 |
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| Name: | Serine/threonine-protein kinase 26 |
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| Synonyms: | MASK | MST4 | STK26 | STK26_HUMAN | Serine/threonine-protein kinase MST4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46517.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1510631 |
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| Residue: | 416 |
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| Sequence: | MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEA
EDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQ
IATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV
GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLV
GDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHS
DDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSCLSMIITPA
FAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQKCSADESP
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| BDBM451739 |
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| n/a |
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| Name | BDBM451739 |
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| Synonyms: | 4-(6-amino-5-(1-oxo-1,2,3,4- tetrahydroisoquinolin-6- yl)pyridin-3-yl)-N- cyclopropyl-3- methoxybenzenesulfonamide | US10710978, Compound I-49 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N4O4S |
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| Mol. Mass. | 464.537 |
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| SMILES | COc1cc(ccc1-c1cnc(N)c(c1)-c1ccc2C(=O)NCCc2c1)S(=O)(=O)NC1CC1 |
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| Structure | 
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