| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 2, facilitated glucose transporter member 1 |
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| Ligand | BDBM453216 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ATP Assay |
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| IC50 | 55±n/a nM |
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| Citation |  Olszewski, K; Poyurovsky, M; Barsotti, A; Kim, J; Liu, KG Treatment of infectious diseases with glucose uptake inhibitors US Patent US10729691 Publication Date 8/4/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 2, facilitated glucose transporter member 1 |
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| Name: | Solute carrier family 2, facilitated glucose transporter member 1 |
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| Synonyms: | GLUT-1 | GLUT1 | GTR1_HUMAN | Glucose Transporter 1 (hGLUT1) | Glucose transporter | Glucose transporter type 1, erythrocyte/brain | HepG2 glucose transporter | SLC2A1 |
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| Type: | Protein |
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| Mol. Mass.: | 54091.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 492 |
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| Sequence: | MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
ELFHPLGADSQV
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| BDBM453216 |
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| n/a |
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| Name | BDBM453216 |
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| Synonyms: | 2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-isobutyryl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenoxy)-N-isopropylacetamide | US10729691, Example 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H35N7O3 |
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| Mol. Mass. | 553.6547 |
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| SMILES | CC(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C(=O)C(C)C |
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| Structure | 
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