| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2B |
|---|
| Ligand | BDBM50373192 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | 5-HT2B Agonist Activity Assay |
|---|
| EC50 | 2900±n/a nM |
|---|
| Citation |  Jensen, KG; Kværnø, L; Jørgensen, M; Juhl, M Catecholamine prodrugs for use in the treatment of Parkinson's disease US Patent US10729710 Publication Date 8/4/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2B |
|---|
| Name: | 5-hydroxytryptamine receptor 2B |
|---|
| Synonyms: | 5-HT2 | 5-HT2B | 5-hydroxytryptamine receptor 2B | 5-hydroxytryptamine receptor 2B (5HT2B) | 5HT2B_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2b |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 53610.91 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | Q02152 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLI
LAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIW
PLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWL
ISIGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTI
HTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETL
MRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTL
LEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSM
VENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI
|
|
|
|---|
| BDBM50373192 |
|---|
| n/a |
|---|
| Name | BDBM50373192 |
|---|
| Synonyms: | CHEMBL405519 | US10729710, Compound (I) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H23NO2 |
|---|
| Mol. Mass. | 261.3593 |
|---|
| SMILES | CCCN1CCC[C@@H]2Cc3c(C[C@@H]12)ccc(O)c3O |
|---|
| Structure | 
|
|---|
Search and Browse
