| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2B |
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| Ligand | BDBM453277 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | 5-HT2B Agonist Activity Assay |
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| EC50 | 3.80±n/a nM |
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| Citation |  Jensen, KG; Kværnø, L; Jørgensen, M; Juhl, M Catecholamine prodrugs for use in the treatment of Parkinson's disease US Patent US10729710 Publication Date 8/4/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2B |
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| Name: | 5-hydroxytryptamine receptor 2B |
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| Synonyms: | 5-HT2 | 5-HT2B | 5-hydroxytryptamine receptor 2B | 5-hydroxytryptamine receptor 2B (5HT2B) | 5HT2B_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2b |
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| Type: | Enzyme |
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| Mol. Mass.: | 53610.91 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q02152 |
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| Residue: | 479 |
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| Sequence: | MASSYKMSEQSTTSEHILQKTCDHLILTNRSGLETDSVAEEMKQTVEGQGHTVHWAALLI
LAVIIPTIGGNILVILAVALEKRLQYATNYFLMSLAIADLLVGLFVMPIALLTIMFEAIW
PLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRATAFIKITVVWL
ISIGIAIPVPIKGIETDVINPHNVTCELTKDRFGSFMVFGSLAAFFAPLTIMVVTYFLTI
HTLQKKAYLVKNKPPQRLTRWTVPTVFLREDSSFSSPEKVAMLDGSHRDKILPNSSDETL
MRRMSSVGKRSAQTISNEQRASKALGVVFFLFLLMWCPFFITNLTLALCDSCNQTTLKTL
LEIFVWIGYVSSGVNPLIYTLFNKTFREAFGRYITCNYRATKSVKALRKFSSTLCFGNSM
VENSKFFTKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLTENDGDKAEEQVSYI
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| BDBM453277 |
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| n/a |
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| Name | BDBM453277 |
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| Synonyms: | US10729710, Compound (Ib) |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23NO2 |
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| Mol. Mass. | 273.37 |
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| SMILES | CCCN1CCC[C@@H]2Cc3c4OCOc4ccc3C[C@@H]12 |r| |
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| Structure | 
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