| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-arginine deiminase type-1 |
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| Ligand | BDBM454160 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 64000±4200 nM |
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| Citation |  Kotra, LP; Wasilewski, E Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof US Patent US10716791 Publication Date 7/21/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-arginine deiminase type-1 |
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| Name: | Protein-arginine deiminase type-1 |
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| Synonyms: | PAD1 | PADI1 | PADI1_HUMAN | PDI1 | Peptidylarginine deiminase I | Protein-arginine deiminase type I |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74664.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1290380 |
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| Residue: | 663 |
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| Sequence: | MAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVK
EPIGKARWPLDTDADMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLE
VDTGRTGKVKRSQGDKKTWRWGPEGYGAILLVNCDRDNHRSAEPDLTHSWLMSLADLQDM
SPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCLSYEVER
QPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGTLPEVTLFTDTVGFRMAPWIMTPNT
QPPEELYVCRVMDTHGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEFGYIE
APHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYVTREIPLPGPSSLDSFGNLDVSPPVTV
GGTEYPLGRILIGSSFPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVDEFLTFV
PTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRHLQRDN
LHAQKCIDWNRNVLKRELGLAESDIVDIPQLFFLKNFYAEAFFPDMVNMVVLGKYLGIPK
PYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYLSYHELQGEIHCGTNVRRKPFPFKWWN
MVP
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| BDBM454160 |
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| n/a |
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| Name | BDBM454160 |
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| Synonyms: | US10716791, Code KP-224 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H29N3O3S |
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| Mol. Mass. | 331.474 |
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| SMILES | S.COC(=O)[C@H](CN1CCNCC1)NC(=O)C1CCCCC1 |r| |
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| Structure | 
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