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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase Tec | ||
| Ligand | BDBM458232 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Inhibition Assay | ||
| IC50 | 1.31±n/a nM | ||
| Citation |  Laurent, A; Morris, SJ Spirocyclic containing compounds and pharmaceutical uses thereof US Patent US10752615 Publication Date 8/25/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase Tec | |||
| Name: | Tyrosine-protein kinase Tec | ||
| Synonyms: | PSCTK4 | TEC | TEC_HUMAN | Tyrosine-protein kinase TEC (TEC) | ||
| Type: | Protein | ||
| Mol. Mass.: | 73597.00 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 631 | ||
| Sequence: |
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| BDBM458232 | |||
| n/a | |||
| Name | BDBM458232 | ||
| Synonyms: | US10752615, Compound 130 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H24F2N4O3S | ||
| Mol. Mass. | 486.534 | ||
| SMILES | OCC(F)(F)c1ccc(s1)C(=O)Nc1nc2ccccc2n1[C@H]1C[C@]2(C1)CCN(C2)C(=O)C=C |r,wU:22.24,24.27,(6.89,1.5,;5.55,2.27,;5.55,3.81,;7.04,3.41,;6.64,4.9,;4.22,4.58,;4.22,6.12,;2.75,6.6,;1.85,5.35,;2.75,4.11,;.31,5.35,;-.46,6.68,;-.46,4.02,;-2,4.02,;-2.91,5.26,;-4.37,4.79,;-5.71,5.56,;-7.04,4.79,;-7.04,3.25,;-5.71,2.48,;-4.37,3.25,;-2.91,2.77,;-2.51,1.28,;-1.17,.51,;-1.94,-.82,;-3.28,-.05,;-.48,-1.3,;-.48,-2.84,;-1.94,-3.31,;-2.85,-2.07,;-2.34,-4.8,;-1.25,-5.89,;-3.83,-5.2,;-4.23,-6.68,)| | ||
| Structure | 
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