| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM458588 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Activity Assay |
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| Ki | 0.100±n/a nM |
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| Citation |  Yoshinaga, H; Ikuma, Y; Ikeda, J; Adachi, S; Mitsunuma, H; Aihara, Y; Besnard, J; Bell, AS Condensed lactam derivative US Patent US10745401 Publication Date 8/18/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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|
|
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| BDBM458588 |
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| n/a |
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| Name | BDBM458588 |
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| Synonyms: | US10745401, Example 62 | US11466007, Example 62 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22BrN5OS |
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| Mol. Mass. | 472.401 |
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| SMILES | Brc1cc2CCN(CCN3CCN(CC3)c3nsc4ccccc34)C(=O)c2cn1 |
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| Structure | 
|
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